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On-going Mechanical Damage from Mastication Drives Homeostatic Th17 Cell Responses at the Oral Barrier

Immuno-surveillance networks operating at barrier sites are tuned by local tissue cues to ensure effective immunity. Site-specific commensal bacteria provide key signals ensuring host defense in the skin and gut. However, how the oral microbiome and tissue-specific signals balance immunity and regul...

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Detalles Bibliográficos
Autores principales: Dutzan, Nicolas, Abusleme, Loreto, Bridgeman, Hayley, Greenwell-Wild, Teresa, Zangerle-Murray, Tamsin, Fife, Mark E., Bouladoux, Nicolas, Linley, Holly, Brenchley, Laurie, Wemyss, Kelly, Calderon, Gloria, Hong, Bo-Young, Break, Timothy J., Bowdish, Dawn M.E., Lionakis, Michail S., Jones, Simon A., Trinchieri, Giorgio, Diaz, Patricia I., Belkaid, Yasmine, Konkel, Joanne E., Moutsopoulos, Niki M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5263257/
https://www.ncbi.nlm.nih.gov/pubmed/28087239
http://dx.doi.org/10.1016/j.immuni.2016.12.010