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Epidemiology of cancer in end-stage renal disease dialysis patients: a national cohort study in Taiwan

The incidence and mortality of site-specific cancers in patients with end-stage renal disease (ESRD) on maintenance dialysis have been rarely studied for Asian populations. We tapped Taiwan`s National Health Insurance Research Database to identify and recruit patients starting maintenance dialysis b...

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Autores principales: Chien, Chih-Chiang, Han, Ming-Ming, Chiu, Yu-Hsien, Wang, Jhi-Joung, Chu, Chin-Chen, Hung, Chien-Ya, Sun, Yih-Min, Yeh, Nai-Cheng, Ho, Chung-Han, Lin, Chih-Ching, Kao, Hao-Yun, Weng, Shih-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5264035/
https://www.ncbi.nlm.nih.gov/pubmed/28123593
http://dx.doi.org/10.7150/jca.16550
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author Chien, Chih-Chiang
Han, Ming-Ming
Chiu, Yu-Hsien
Wang, Jhi-Joung
Chu, Chin-Chen
Hung, Chien-Ya
Sun, Yih-Min
Yeh, Nai-Cheng
Ho, Chung-Han
Lin, Chih-Ching
Kao, Hao-Yun
Weng, Shih-Feng
author_facet Chien, Chih-Chiang
Han, Ming-Ming
Chiu, Yu-Hsien
Wang, Jhi-Joung
Chu, Chin-Chen
Hung, Chien-Ya
Sun, Yih-Min
Yeh, Nai-Cheng
Ho, Chung-Han
Lin, Chih-Ching
Kao, Hao-Yun
Weng, Shih-Feng
author_sort Chien, Chih-Chiang
collection PubMed
description The incidence and mortality of site-specific cancers in patients with end-stage renal disease (ESRD) on maintenance dialysis have been rarely studied for Asian populations. We tapped Taiwan`s National Health Insurance Research Database to identify and recruit patients starting maintenance dialysis between 1999 and 2004. They were followed from initiation of dialysis until death, discontinuation of dialysis, or the end of 2008. We calculated the survival rate and mortality risk of dialysis patients with cancer. Of 40,833 dialysis patients, 2352 (5.8%) had been newly diagnosed with cancer. Being older, being male, and having chronic liver disease were factors associated with a higher risk for new cancer in ESRD dialysis patients. In men, liver cancer (20.63%) was the most frequent, followed by cancers of the bladder (16.88%) and kidney (11.61%). In women, bladder cancer (25.57%) was the most frequent, followed by cancers of the kidney (16.31%) and breast (11.20%). The 5-year survival rates for kidney and bladder cancer were higher than for other cancers; the survival rates for lung, stomach, and liver cancer were lower. In conclusion, the distribution of site-specific cancer was different between men and women in patients with ESRD on dialysis. More attention should be paid to teaching dialysis patients how to avoid the well-known cancer risks and carcinogens and individualized regular cancer screenings.
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spelling pubmed-52640352017-01-25 Epidemiology of cancer in end-stage renal disease dialysis patients: a national cohort study in Taiwan Chien, Chih-Chiang Han, Ming-Ming Chiu, Yu-Hsien Wang, Jhi-Joung Chu, Chin-Chen Hung, Chien-Ya Sun, Yih-Min Yeh, Nai-Cheng Ho, Chung-Han Lin, Chih-Ching Kao, Hao-Yun Weng, Shih-Feng J Cancer Research Paper The incidence and mortality of site-specific cancers in patients with end-stage renal disease (ESRD) on maintenance dialysis have been rarely studied for Asian populations. We tapped Taiwan`s National Health Insurance Research Database to identify and recruit patients starting maintenance dialysis between 1999 and 2004. They were followed from initiation of dialysis until death, discontinuation of dialysis, or the end of 2008. We calculated the survival rate and mortality risk of dialysis patients with cancer. Of 40,833 dialysis patients, 2352 (5.8%) had been newly diagnosed with cancer. Being older, being male, and having chronic liver disease were factors associated with a higher risk for new cancer in ESRD dialysis patients. In men, liver cancer (20.63%) was the most frequent, followed by cancers of the bladder (16.88%) and kidney (11.61%). In women, bladder cancer (25.57%) was the most frequent, followed by cancers of the kidney (16.31%) and breast (11.20%). The 5-year survival rates for kidney and bladder cancer were higher than for other cancers; the survival rates for lung, stomach, and liver cancer were lower. In conclusion, the distribution of site-specific cancer was different between men and women in patients with ESRD on dialysis. More attention should be paid to teaching dialysis patients how to avoid the well-known cancer risks and carcinogens and individualized regular cancer screenings. Ivyspring International Publisher 2017-01-01 /pmc/articles/PMC5264035/ /pubmed/28123593 http://dx.doi.org/10.7150/jca.16550 Text en © Ivyspring International Publisher. This is an open access article distributed under the terms of the Creative Commons Attribution (CC BY-NC) license (https://creativecommons.org/licenses/by-nc/4.0/). See http://ivyspring.com/terms for full terms and conditions.
spellingShingle Research Paper
Chien, Chih-Chiang
Han, Ming-Ming
Chiu, Yu-Hsien
Wang, Jhi-Joung
Chu, Chin-Chen
Hung, Chien-Ya
Sun, Yih-Min
Yeh, Nai-Cheng
Ho, Chung-Han
Lin, Chih-Ching
Kao, Hao-Yun
Weng, Shih-Feng
Epidemiology of cancer in end-stage renal disease dialysis patients: a national cohort study in Taiwan
title Epidemiology of cancer in end-stage renal disease dialysis patients: a national cohort study in Taiwan
title_full Epidemiology of cancer in end-stage renal disease dialysis patients: a national cohort study in Taiwan
title_fullStr Epidemiology of cancer in end-stage renal disease dialysis patients: a national cohort study in Taiwan
title_full_unstemmed Epidemiology of cancer in end-stage renal disease dialysis patients: a national cohort study in Taiwan
title_short Epidemiology of cancer in end-stage renal disease dialysis patients: a national cohort study in Taiwan
title_sort epidemiology of cancer in end-stage renal disease dialysis patients: a national cohort study in taiwan
topic Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5264035/
https://www.ncbi.nlm.nih.gov/pubmed/28123593
http://dx.doi.org/10.7150/jca.16550
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