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Icariside II, a novel phosphodiesterase 5 inhibitor, protects against H(2)O(2)‐induced PC12 cells death by inhibiting mitochondria‐mediated autophagy

Oxidative stress is a major cause of cellular injury in a variety of human diseases including neurodegenerative disorders. Thus, removal of excessive reactive oxygen species (ROS) or suppression of ROS generation may be effective in preventing oxidative stress‐induced cell death. This study was desi...

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Detalles Bibliográficos
Autores principales: Gao, Jianmei, Deng, Yuanyuan, Yin, Caixia, Liu, Yuangui, Zhang, Wei, Shi, Jingshan, Gong, Qihai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5264130/
https://www.ncbi.nlm.nih.gov/pubmed/27642051
http://dx.doi.org/10.1111/jcmm.12971

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