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Icariside II, a novel phosphodiesterase 5 inhibitor, protects against H(2)O(2)‐induced PC12 cells death by inhibiting mitochondria‐mediated autophagy
Oxidative stress is a major cause of cellular injury in a variety of human diseases including neurodegenerative disorders. Thus, removal of excessive reactive oxygen species (ROS) or suppression of ROS generation may be effective in preventing oxidative stress‐induced cell death. This study was desi...
Autores principales: | Gao, Jianmei, Deng, Yuanyuan, Yin, Caixia, Liu, Yuangui, Zhang, Wei, Shi, Jingshan, Gong, Qihai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5264130/ https://www.ncbi.nlm.nih.gov/pubmed/27642051 http://dx.doi.org/10.1111/jcmm.12971 |
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