High frequency of antidrug antibodies and association of random drug levels with efficacy in certolizumab pegol-treated patients with rheumatoid arthritis: results from the BRAGGSS cohort

OBJECTIVES: To evaluate (i) the association between random certolizumab drug levels, antidrug antibodies (ADAbs) and treatment response in patients with rheumatoid arthritis (RA); (ii) longitudinal factors associated with ADAbs and certolizumab drug levels. METHODS: This prospective cohort included...

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Detalles Bibliográficos
Autores principales: Jani, Meghna, Isaacs, John D, Morgan, Ann W, Wilson, Anthony G, Plant, Darren, Hyrich, Kimme L, Chinoy, Hector, Barton, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2017
Materias:
Clinical and Epidemiological Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5264213/
https://www.ncbi.nlm.nih.gov/pubmed/27245864
http://dx.doi.org/10.1136/annrheumdis-2015-208849

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5264213/
https://www.ncbi.nlm.nih.gov/pubmed/27245864
http://dx.doi.org/10.1136/annrheumdis-2015-208849

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