Inhibition of G0/G1 Switch 2 Ameliorates Renal Inflammation in Chronic Kidney Disease

Chronic kidney disease (CKD) is a global health problem, and novel therapies to treat CKD are urgently needed. Here, we show that inhibition of G(0)/G(1) switch 2 (G0s2) ameliorates renal inflammation in a mouse model of CKD. Renal expression of chemokine (C-C motif) ligand 2 (Ccl2) was increased in...

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Detalles Bibliográficos
Autores principales: Matsunaga, Naoya, Ikeda, Eriko, Kakimoto, Keisuke, Watanabe, Miyako, Shindo, Naoya, Tsuruta, Akito, Ikeyama, Hisako, Hamamura, Kengo, Higashi, Kazuhiro, Yamashita, Tomohiro, Kondo, Hideaki, Yoshida, Yuya, Matsuda, Masaki, Ogino, Takashi, Tokushige, Kazutaka, Itcho, Kazufumi, Furuichi, Yoko, Nakao, Takaharu, Yasuda, Kaori, Doi, Atsushi, Amamoto, Toshiaki, Aramaki, Hironori, Tsuda, Makoto, Inoue, Kazuhide, Ojida, Akio, Koyanagi, Satoru, Ohdo, Shigehiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5264248/
https://www.ncbi.nlm.nih.gov/pubmed/27745900
http://dx.doi.org/10.1016/j.ebiom.2016.10.008

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