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G Protein-coupled Receptor Kinase 2 (GRK2) Promotes Breast Tumorigenesis Through a HDAC6-Pin1 Axis

In addition to oncogenic drivers, signaling nodes can critically modulate cancer-related cellular networks to strength tumor hallmarks. We identify G-protein-coupled receptor kinase 2 (GRK2) as a relevant player in breast cancer. GRK2 is up-regulated in breast cancer cell lines, in spontaneous tumor...

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Detalles Bibliográficos
Autores principales:	Nogués, Laura, Reglero, Clara, Rivas, Verónica, Salcedo, Alicia, Lafarga, Vanesa, Neves, Maria, Ramos, Paula, Mendiola, Marta, Berjón, Alberto, Stamatakis, Kostas, Zhou, Xiao Zhen, Lu, Kun Ping, Hardisson, David, Mayor, Federico, Penela, Petronila
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5264252/ https://www.ncbi.nlm.nih.gov/pubmed/27720394 http://dx.doi.org/10.1016/j.ebiom.2016.09.030

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