Deformed Skull Morphology Is Caused by the Combined Effects of the Maldevelopment of Calvarias, Cranial Base and Brain in FGFR2-P253R Mice Mimicking Human Apert Syndrome

Apert syndrome (AS) is a common genetic syndrome in humans characterized with craniosynostosis. Apert patients and mouse models showed abnormalities in sutures, cranial base and brain, that may all be involved in the pathogenesis of skull malformation of Apert syndrome. To distinguish the differenti...

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Detalles Bibliográficos
Autores principales: Luo, Fengtao, Xie, Yangli, Xu, Wei, Huang, Junlan, Zhou, Siru, Wang, Zuqiang, Luo, Xiaoqing, Liu, Mi, Chen, Lin, Du, Xiaolan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5264259/
https://www.ncbi.nlm.nih.gov/pubmed/28123344
http://dx.doi.org/10.7150/ijbs.16287

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