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Pigment Epithelium-Derived Factor (PEDF) mediates cartilage matrix loss in an age-dependent manner under inflammatory conditions

BACKGROUND: Inflammation is a major cause of cartilage destruction and leads to the imbalance of metabolic activities in the arthritic joint. Pigment epithelium-derived factor (PEDF) has been reported to have both pro- and anti-inflammatory activities in various cell types and to be upregulated in t...

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Detalles Bibliográficos
Autores principales:	Nakamura, Daisy S., Hollander, Judith M., Uchimura, Tomoya, Nielsen, Heber C., Zeng, Li
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5264335/ https://www.ncbi.nlm.nih.gov/pubmed/28122611 http://dx.doi.org/10.1186/s12891-017-1410-y

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