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Using the fragment molecular orbital method to investigate agonist–orexin-2 receptor interactions
The understanding of binding interactions between any protein and a small molecule plays a key role in the rationalization of affinity and selectivity and is essential for an efficient structure-based drug discovery (SBDD) process. Clearly, to begin SBDD, a structure is needed, and although there ha...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Portland Press Ltd.
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5264495/ https://www.ncbi.nlm.nih.gov/pubmed/27068972 http://dx.doi.org/10.1042/BST20150250 |