Cargando…
Computational protein design with backbone plasticity
The computational algorithms used in the design of artificial proteins have become increasingly sophisticated in recent years, producing a series of remarkable successes. The most dramatic of these is the de novo design of artificial enzymes. The majority of these designs have reused naturally occur...
Autores principales: | MacDonald, James T., Freemont, Paul S. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5264498/ https://www.ncbi.nlm.nih.gov/pubmed/27911735 http://dx.doi.org/10.1042/BST20160155 |
Ejemplares similares
-
Validation of an entirely in vitro approach for rapid prototyping of DNA regulatory elements for synthetic biology
por: Chappell, James, et al.
Publicado: (2013) -
Synthetic biology: biology by design
por: Roberts, M. A. J., et al.
Publicado: (2013) -
De novo backbone scaffolds for protein design
por: MacDonald, James T, et al.
Publicado: (2010) -
Computationally-guided design and selection of high performing ribosomal active site mutants
por: Kofman, Camila, et al.
Publicado: (2022) -
The geometric influence on the Cys(2)His(2) zinc finger domain and functional plasticity
por: Mueller, April L, et al.
Publicado: (2020)