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Fenofibrate Inhibits Cytochrome P450 Epoxygenase 2C Activity to Suppress Pathological Ocular Angiogenesis
Neovascular eye diseases including retinopathy of prematurity, diabetic retinopathy and age-related-macular-degeneration are major causes of blindness. Fenofibrate treatment in type 2 diabetes patients reduces progression of diabetic retinopathy independent of its peroxisome proliferator-activated r...
Autores principales: | Gong, Yan, Shao, Zhuo, Fu, Zhongjie, Edin, Matthew L., Sun, Ye, Liegl, Raffael G., Wang, Zhongxiao, Liu, Chi-Hsiu, Burnim, Samuel B., Meng, Steven S., Lih, Fred B., SanGiovanni, John Paul, Zeldin, Darryl C., Hellström, Ann, Smith, Lois E.H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5264653/ https://www.ncbi.nlm.nih.gov/pubmed/27720395 http://dx.doi.org/10.1016/j.ebiom.2016.09.025 |
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