Soft tissue Rosai–Dorfman disease in child: A case report and literature review

BACKGROUND: Rosai–Dorfman disease was commonly characterized as massive, painless, bilateral, symmetric cervical lymphadenopathy, with fever, leukocytosis, and elevated sedimentation rate. However, soft tissue Rosai–Dorfman disease (STRDD) is a rare benign tumor. METHODS: We hereby present 1 case of...

Descripción completa

Detalles Bibliográficos
Autores principales: Xu, Yunlan, Han, Bingqiang, Yang, Jie, Ma, Jing, Chen, Ji, Wang, Zhigang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2016
Materias:
5700
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5265751/
https://www.ncbi.nlm.nih.gov/pubmed/27442634
http://dx.doi.org/10.1097/MD.0000000000004021
Descripción
Sumario:BACKGROUND: Rosai–Dorfman disease was commonly characterized as massive, painless, bilateral, symmetric cervical lymphadenopathy, with fever, leukocytosis, and elevated sedimentation rate. However, soft tissue Rosai–Dorfman disease (STRDD) is a rare benign tumor. METHODS: We hereby present 1 case of a 17-month-old girl, an isolated subcutaneous mass was detected on her right forearm, and no signs of pain, swelling, or erythema were observed at the site. RESULTS: The patient underwent an excisional biopsy for the mass. Immunohistochemistry results showed that it was positive for S-100 protein and CD68, whereas negative for CD1a, which supported the diagnosis of STRDD. Conclusions: The patient showed no evidence of recurrence or metastasis 2 years after the surgery. Some multifocal masses were reported to be much more prone to recurrence. Further follow-up of STRDD is necessary.

Ejemplares similares