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Complement activation and effect of eculizumab in scleroderma renal crisis

BACKGROUND: Scleroderma renal crisis (SRC) is a life-threatening complication of systemic sclerosis characterized by abrupt onset of hypertension, thrombotic microangiopathy, and kidney injury. The mechanisms of the disease remain ill-defined, but a growing body of evidence suggests that activation...

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Detalles Bibliográficos
Autores principales:	Devresse, Arnaud, Aydin, Selda, Le Quintrec, Moglie, Demoulin, Nathalie, Stordeur, Patrick, Lambert, Catherine, Gastoldi, Sara, Pirson, Yves, Jadoul, Michel, Morelle, Johann
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Wolters Kluwer Health 2016
Materias:	5200
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5265879/ https://www.ncbi.nlm.nih.gov/pubmed/27472742 http://dx.doi.org/10.1097/MD.0000000000004459

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