Post-Translational Dosage Compensation Buffers Genetic Perturbations to Stoichiometry of Protein Complexes

Understanding buffering mechanisms for various perturbations is essential for understanding robustness in cellular systems. Protein-level dosage compensation, which arises when changes in gene copy number do not translate linearly into protein level, is one mechanism for buffering against genetic pe...

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Detalles Bibliográficos
Autores principales: Ishikawa, Koji, Makanae, Koji, Iwasaki, Shintaro, Ingolia, Nicholas T., Moriya, Hisao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5266272/
https://www.ncbi.nlm.nih.gov/pubmed/28121980
http://dx.doi.org/10.1371/journal.pgen.1006554

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5266272/
https://www.ncbi.nlm.nih.gov/pubmed/28121980
http://dx.doi.org/10.1371/journal.pgen.1006554

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