Cargando…
Negative Immune Regulator TIPE2 Promotes M2 Macrophage Differentiation through the Activation of PI3K-AKT Signaling Pathway
Macrophages play important roles in the regulation of the innate and adaptive immune responses. Classically activated macrophages and alternatively activated macrophages are the two major forms of macrophages and have opposing functionalities. Tumor necrosis factor-α-induced protein 8–2 is expressed...
Autores principales: | Liu, Ruiling, Fan, Tingting, Geng, Wenwen, Chen, Youhai H., Ruan, Qingguo, Zhang, Cui |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5266285/ https://www.ncbi.nlm.nih.gov/pubmed/28122045 http://dx.doi.org/10.1371/journal.pone.0170666 |
Ejemplares similares
-
Loss of TIPE2 Has Opposing Effects on the Pathogenesis of Autoimmune Diseases
por: Liu, Ruiling, et al.
Publicado: (2019) -
TIPE2 specifies the functional polarization of myeloid-derived suppressor cells during tumorigenesis
por: Yan, Dehong, et al.
Publicado: (2019) -
TIPE2 governs macrophage polarization via negative regulation of mTORC1
por: Jiang, Yuan, et al.
Publicado: (2018) -
TIPE2 inhibits PDGF-BB-induced phenotype switching in airway smooth muscle cells through the PI3K/Akt signaling pathway
por: Wang, Huiyuan, et al.
Publicado: (2021) -
TIPE2 Overexpression Suppresses the Proliferation, Migration, and Invasion in Prostate Cancer Cells by Inhibiting PI3K/Akt Signaling Pathway
por: Lu, Qiang, et al.
Publicado: (2016)