Rheumatic Heart Disease and Myxomatous Degeneration: Differences and Similarities of Valve Damage Resulting from Autoimmune Reactions and Matrix Disorganization

Autoimmune inflammatory reactions leading to rheumatic fever (RF) and rheumatic heart disease (RHD) result from untreated Streptococcus pyogenes throat infections in individuals who exhibit genetic susceptibility. Immune effector mechanisms have been described that lead to heart tissue damage culmin...

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Detalles Bibliográficos
Autores principales: Martins, Carlo de Oliveira, Demarchi, Lea, Ferreira, Frederico Moraes, Pomerantzeff, Pablo Maria Alberto, Brandao, Carlos, Sampaio, Roney Orismar, Spina, Guilherme Sobreira, Kalil, Jorge, Cunha-Neto, Edecio, Guilherme, Luiza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5266332/
https://www.ncbi.nlm.nih.gov/pubmed/28121998
http://dx.doi.org/10.1371/journal.pone.0170191

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