Cargando…
Recurrent acute portal vein thrombosis in liver cirrhosis treated by rivaroxaban
Cirrhosis can occur with the development of portal vein thrombosis (PVT). PVT may aggravate portal hypertension, and it can lead to hepatic decompensation. The international guideline recommends for anticoagulation treatment to be maintained for at least 3 months in all patients with acute PVT. Low-...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Association for the Study of the Liver
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5266341/ https://www.ncbi.nlm.nih.gov/pubmed/27880998 http://dx.doi.org/10.3350/cmh.2016.0016 |
_version_ | 1782500450642165760 |
---|---|
author | Yang, Hyeyoung Kim, Seo Ree Song, Myeong Jun |
author_facet | Yang, Hyeyoung Kim, Seo Ree Song, Myeong Jun |
author_sort | Yang, Hyeyoung |
collection | PubMed |
description | Cirrhosis can occur with the development of portal vein thrombosis (PVT). PVT may aggravate portal hypertension, and it can lead to hepatic decompensation. The international guideline recommends for anticoagulation treatment to be maintained for at least 3 months in all patients with acute PVT. Low-molecular-weight-heparin and changing to warfarin is the usual anticoagulation treatment. However, warfarin therapy is problematic due to a narrow therapeutic window and the requirement for frequent dose adjustment, which has prompted the development of novel oral anticoagulants for overcoming these problems. We report a 63-year-old female who experienced complete resolution of recurrent acute PVT in liver cirrhosis after treatment with rivaroxaban. |
format | Online Article Text |
id | pubmed-5266341 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | The Korean Association for the Study of the Liver |
record_format | MEDLINE/PubMed |
spelling | pubmed-52663412017-01-26 Recurrent acute portal vein thrombosis in liver cirrhosis treated by rivaroxaban Yang, Hyeyoung Kim, Seo Ree Song, Myeong Jun Clin Mol Hepatol Case Report Cirrhosis can occur with the development of portal vein thrombosis (PVT). PVT may aggravate portal hypertension, and it can lead to hepatic decompensation. The international guideline recommends for anticoagulation treatment to be maintained for at least 3 months in all patients with acute PVT. Low-molecular-weight-heparin and changing to warfarin is the usual anticoagulation treatment. However, warfarin therapy is problematic due to a narrow therapeutic window and the requirement for frequent dose adjustment, which has prompted the development of novel oral anticoagulants for overcoming these problems. We report a 63-year-old female who experienced complete resolution of recurrent acute PVT in liver cirrhosis after treatment with rivaroxaban. The Korean Association for the Study of the Liver 2016-12 2016-11-25 /pmc/articles/PMC5266341/ /pubmed/27880998 http://dx.doi.org/10.3350/cmh.2016.0016 Text en Copyright © 2016 by The Korean Association for the Study of the Liver This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Yang, Hyeyoung Kim, Seo Ree Song, Myeong Jun Recurrent acute portal vein thrombosis in liver cirrhosis treated by rivaroxaban |
title | Recurrent acute portal vein thrombosis in liver cirrhosis treated by rivaroxaban |
title_full | Recurrent acute portal vein thrombosis in liver cirrhosis treated by rivaroxaban |
title_fullStr | Recurrent acute portal vein thrombosis in liver cirrhosis treated by rivaroxaban |
title_full_unstemmed | Recurrent acute portal vein thrombosis in liver cirrhosis treated by rivaroxaban |
title_short | Recurrent acute portal vein thrombosis in liver cirrhosis treated by rivaroxaban |
title_sort | recurrent acute portal vein thrombosis in liver cirrhosis treated by rivaroxaban |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5266341/ https://www.ncbi.nlm.nih.gov/pubmed/27880998 http://dx.doi.org/10.3350/cmh.2016.0016 |
work_keys_str_mv | AT yanghyeyoung recurrentacuteportalveinthrombosisinlivercirrhosistreatedbyrivaroxaban AT kimseoree recurrentacuteportalveinthrombosisinlivercirrhosistreatedbyrivaroxaban AT songmyeongjun recurrentacuteportalveinthrombosisinlivercirrhosistreatedbyrivaroxaban |