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Paired Primary and Metastatic Tumor Analysis of Somatic Mutations in Synchronous and Metachronous Colorectal Cancer
PURPOSE: Although the mutation status of KRAS is highly concordant in primary and metastatic lesions, it has not been generalized to other major pathway genes. MATERIALS AND METHODS: In this study, 41 genes were evaluated and the mutational profiles were compared in 46 colorectal cancer patients wit...
Autores principales: | Kim, Kyu-pyo, Kim, Jeong-Eun, Hong, Yong Sang, Ahn, Sung-Min, Chun, Sung Min, Hong, Seung-Mo, Jang, Se Jin, Yu, Chang Sik, Kim, Jin Cheon, Kim, Tae Won |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Cancer Association
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5266409/ https://www.ncbi.nlm.nih.gov/pubmed/27384156 http://dx.doi.org/10.4143/crt.2015.490 |
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