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Immunotherapy with Dendritic Cells Modified with Tumor-Associated Antigen Gene Demonstrates Enhanced Antitumor Effect Against Lung Cancer()

BACKGROUND: Immunotherapy using dendritic cell (DC) vaccine has the potential to overcome the bottleneck of cancer therapy. METHODS: We engineered Lewis lung cancer cells (LLCs) and bone marrow–derived DCs to express tumor-associated antigen (TAA) ovalbumin (OVA) via lentiviral vector plasmid encodi...

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Detalles Bibliográficos
Autores principales:	Jiang, Tao, Chen, Xiao, Zhou, Wei, Fan, Guoxin, Zhao, Peilin, Ren, Shengxiang, Zhou, Caicun, Zhang, Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Neoplasia Press 2017
Materias:	Original article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5266489/ https://www.ncbi.nlm.nih.gov/pubmed/28129580 http://dx.doi.org/10.1016/j.tranon.2016.12.002

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