Pho4 Is Essential for Dissemination of Cryptococcus neoformans to the Host Brain by Promoting Phosphate Uptake and Growth at Alkaline pH

Phosphate acquisition by fungi is regulated by the phosphate-sensing and acquisition (PHO) signaling pathway. Cryptococcus neoformans disseminates from the lung to the brain and is the commonest cause of fungal meningitis worldwide. To investigate the contribution of PHO signaling to cryptococcal di...

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Detalles Bibliográficos
Autores principales: Lev, Sophie, Kaufman-Francis, Keren, Desmarini, Desmarini, Juillard, Pierre G., Li, Cecilia, Stifter, Sebastian A., Feng, Carl G., Sorrell, Tania C., Grau, Georges E. R., Bahn, Yong-Sun, Djordjevic, Julianne T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5266496/
https://www.ncbi.nlm.nih.gov/pubmed/28144629
http://dx.doi.org/10.1128/mSphere.00381-16

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