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Putatively novel serotypes and the potential for reduced vaccine effectiveness: capsular locus diversity revealed among 5405 pneumococcal genomes

The pneumococcus is a leading global pathogen and a key virulence factor possessed by the majority of pneumococci is an antigenic polysaccharide capsule (‘serotype’), which is encoded by the capsular (cps) locus. Approximately 100 different serotypes are known, but the extent of sequence diversity w...

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Detalles Bibliográficos
Autores principales:	van Tonder, Andries J., Bray, James E., Quirk, Sigríður J., Haraldsson, Gunnsteinn, Jolley, Keith A., Maiden, Martin C. J., Hoffmann, Steen, Bentley, Stephen D., Haraldsson, Ásgeir, Erlendsdóttir, Helga, Kristinsson, Karl G., Brueggemann, Angela B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Microbiology Society 2016
Materias:	BioResource
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5266551/ https://www.ncbi.nlm.nih.gov/pubmed/28133541 http://dx.doi.org/10.1099/mgen.0.000090

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