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Fc Engineering for Developing Therapeutic Bispecific Antibodies and Novel Scaffolds

Therapeutic monoclonal antibodies have become molecules of choice to treat autoimmune disorders, inflammatory diseases, and cancer. Moreover, bispecific/multispecific antibodies that target more than one antigen or epitope on a target cell or recruit effector cells (T cell, natural killer cell, or m...

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Detalles Bibliográficos
Autores principales: Liu, Hongyan, Saxena, Abhishek, Sidhu, Sachdev S., Wu, Donghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5266686/
https://www.ncbi.nlm.nih.gov/pubmed/28184223
http://dx.doi.org/10.3389/fimmu.2017.00038