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Identification of Bacterial Surface Antigens by Screening Peptide Phage Libraries Using Whole Bacteria Cell-Purified Antisera

Bacterial surface proteins can be good vaccine candidates. In the present study, we used polyclonal antibodies purified with intact Erysipelothrix rhusiopthiae to screen phage-displayed random dodecapeptide and loop-constrained heptapeptide libraries, which led to the identification of mimotopes. Ho...

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Detalles Bibliográficos
Autores principales: Hu, Yun-Fei, Zhao, Dun, Yu, Xing-Long, Hu, Yu-Li, Li, Run-Cheng, Ge, Meng, Xu, Tian-Qi, Liu, Xiao-Bo, Liao, Hua-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5266700/
https://www.ncbi.nlm.nih.gov/pubmed/28184219
http://dx.doi.org/10.3389/fmicb.2017.00082