IL-1β-Induced Accumulation of Amyloid: Macroautophagy in Skeletal Muscle Depends on ERK

The pathology of inclusion body myositis (IBM) involves an inflammatory response and β-amyloid deposits in muscle fibres. It is believed that MAP kinases such as the ERK signalling pathway mediate the inflammatory signalling in cells. Further, there is evidence that autophagic activity plays a cruci...

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Detalles Bibliográficos
Autores principales: Schmidt, Karsten, Wienken, Magdalena, Keller, Christian W., Balcarek, Peter, Münz, Christian, Schmidt, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5266815/
https://www.ncbi.nlm.nih.gov/pubmed/28167851
http://dx.doi.org/10.1155/2017/5470831

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5266815/
https://www.ncbi.nlm.nih.gov/pubmed/28167851
http://dx.doi.org/10.1155/2017/5470831

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