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Whole-exome sequencing analysis of supernumerary teeth occurrence in Japanese individuals

A common disorder of human dentition is the existence of supernumerary teeth. Impacted supernumerary teeth occur most frequently in the maxillary incisor area and are termed mesiodens. We conducted whole-exome sequencing of non-syndromic Japanese individuals possessing supernumerary teeth to identif...

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Detalles Bibliográficos
Autores principales: Takahashi, Masahiro, Hosomichi, Kazuyoshi, Yamaguchi, Tetsutaro, Yano, Keisuke, Funatsu, Takahiro, Adel, Mohamed, Haga, Shugo, Maki, Koutaro, Tajima, Atsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5267165/
https://www.ncbi.nlm.nih.gov/pubmed/28144447
http://dx.doi.org/10.1038/hgv.2016.46
Descripción
Sumario:A common disorder of human dentition is the existence of supernumerary teeth. Impacted supernumerary teeth occur most frequently in the maxillary incisor area and are termed mesiodens. We conducted whole-exome sequencing of non-syndromic Japanese individuals possessing supernumerary teeth to identify genes and/or loci involved in the pathogenesis of the condition.