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PD-1, PD-L1 (B7-H1) and Tumor-Site Immune Modulation Therapy: The Historical Perspective

The current success of targeted inhibition against cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) and Programmed Death 1/Programmed Death Ligand 1 (PD-1/PD-L1, herein collectively referred to as PD) pathways is hailed as a cancer immunotherapy breakthrough. PD-L1, known also as B7 homolog 1 (B...

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Detalles Bibliográficos
Autores principales:	Wang, Jun, Yuan, Ruirong, Song, Wenru, Sun, Jingwei, Liu, Delong, Li, Zihai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5267378/ https://www.ncbi.nlm.nih.gov/pubmed/28122590 http://dx.doi.org/10.1186/s13045-017-0403-5

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