Cargando…

Uridine stimulate laxative effect in the loperamide-induced constipation of SD rats through regulation of the mAChRs signaling pathway and mucin secretion

BACKGROUND: Uridine (Urd), which has been reported as a major component of RNA, plays an important role in various biological process including neuroprotection, biochemical modulation and glycolysis, although its role in constipation has yet to be established. Therefore, in this study, we investigat...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Ji Eun, Go, Jun, Sung, Ji Eun, Lee, Hyun Ah, Yun, Woo Bin, Hong, Jin Tae, Hwang, Dae Youn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5267432/
https://www.ncbi.nlm.nih.gov/pubmed/28122499
http://dx.doi.org/10.1186/s12876-017-0576-y