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Estimating and accounting for tumor purity in the analysis of DNA methylation data from cancer studies
We present a set of statistical methods for the analysis of DNA methylation microarray data, which account for tumor purity. These methods are an extension of our previously developed method for purity estimation; our updated method is flexible, efficient, and does not require data from reference sa...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5267453/ https://www.ncbi.nlm.nih.gov/pubmed/28122605 http://dx.doi.org/10.1186/s13059-016-1143-5 |