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On the emergence of multifocal cancers
Several tumors can exist as multiple lesions within a tissue. The lesions may either arise independently, or they may be monoclonal. The importance of multiple lesions for tumor staging, progression, and treatment is subject to debate. Here we use mathematical models to analyze the emergence of mult...
Autores principales: | Wodarz, Dominik, Iwasa, Yoh, Komarova, Natalia L |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC526757/ https://www.ncbi.nlm.nih.gov/pubmed/15461783 http://dx.doi.org/10.1186/1477-3163-3-13 |
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