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Serum adiponectin as a biomarker for in vivo PPARgamma activation and PPARgamma agonist-induced efficacy on insulin sensitization/lipid lowering in rats
BACKGROUND: PPARγ agonists ameliorate insulin resistance and dyslipidemia in type 2 diabetic patients. Adiponectin possesses insulin sensitizing properties, and predicts insulin sensitivity of both glucose and lipid metabolism. In diet-induced insulin resistant rats and ZDF rats, the current studies...
Autores principales: | Yang, Baichun, Brown, Kathleen K, Chen, Lihong, Carrick, Kevin M, Clifton, Lisa G, McNulty, Judi A, Winegar, Deborah A, Strum, Jay C, Stimpson, Stephen A, Pahel, Gregory L |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC526775/ https://www.ncbi.nlm.nih.gov/pubmed/15491498 http://dx.doi.org/10.1186/1471-2210-4-23 |
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