Cargando…

Clinicopathologic review of polyps biopsied at colonoscopy in Lagos, Nigeria

INTRODUCTION: Colorectal polyps are known precursors of colorectal cancers. The increase in utilization of colonoscopy in Nigeria has meant a rise in the recently reported incidence of these lesions. The aim of this study is to evaluate the clinicopathological profile of colorectal polyps biopsied d...

Descripción completa

Detalles Bibliográficos
Autores principales: Oluyemi, Aderemi, Awolola, Nicholas, Oyedeji, Olufemi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The African Field Epidemiology Network 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5267854/
https://www.ncbi.nlm.nih.gov/pubmed/28154688
http://dx.doi.org/10.11604/pamj.2016.24.333.9434
_version_ 1782500709130829824
author Oluyemi, Aderemi
Awolola, Nicholas
Oyedeji, Olufemi
author_facet Oluyemi, Aderemi
Awolola, Nicholas
Oyedeji, Olufemi
author_sort Oluyemi, Aderemi
collection PubMed
description INTRODUCTION: Colorectal polyps are known precursors of colorectal cancers. The increase in utilization of colonoscopy in Nigeria has meant a rise in the recently reported incidence of these lesions. The aim of this study is to evaluate the clinicopathological profile of colorectal polyps biopsied during the inaugural 12 month period of colonoscopy from a private endoscopy suite in Nigeria. METHODS: This is a retrospective review of all the clients who had polyps diagnosed at colonoscopy over a 12 month period (August 2014 –July 2015) at a private endoscopy suite in Lagos, Nigeria. This analysis of prospectively collected data was performed using clinical information from the endoscopy logs and pathology database system of a private endoscopy suite based in Lagos, Nigeria. RESULTS: A total of 125 colonoscopies were carried out over the stated period. Of these, 14 individuals had a total of 18 polyps- 4 clients (28.6% of the persons with polyps) had two polyps each. The polyp detection rate was 11.2% while the polyp per colonoscopy rate was 14.4%. Of these clients, males were 10 in number; giving a male to female ratio of 2.5:1. Their ages ranged from 37 to 77 years (mean= 57.3 years). The presenting complaint at colonoscopy was hematochezia in 11 (78.6%), new onset constipation in 2 (14.2%) and peri-anal pain in 1 patient (7.1%). The polyps were distributed as follows; 2 (11.1%) in the ascending colon, 1 (5.6%) each in the transverse and descending colons, 8 (44.4%) in the sigmoid colon, 6(33.3%) located in the rectum. Hence, there was left sided (15 of 18= 83.3%) preponderance. Pathologically, tubular (adenomatous) polyp with or without low grade dysplastic changes was diagnosed in 6 of the 18 polyps (giving an adenoma detection rate of 4.8%), 4 (22.2%) were inflammatory polyps, 1 (5.6%) was malignant and another had the rare inflammatory fibroid polyp. Five (27.8%) of the specimens were reported as non-specific colitis. CONCLUSION: The study supports the present wisdom that polyps are clearly less prevalent in our environment when compared to the Western world. The increased prevalence with advancing age, in male subjects and of left sided lesions, is also in keeping with previous results from our environment. A case is also advanced for the increased deployment of endoscopy as a tool for the detection of these polyps and ultimately, the reduction of colorectal cancer in our population.
format Online
Article
Text
id pubmed-5267854
institution National Center for Biotechnology Information
language English
publishDate 2016
publisher The African Field Epidemiology Network
record_format MEDLINE/PubMed
spelling pubmed-52678542017-02-02 Clinicopathologic review of polyps biopsied at colonoscopy in Lagos, Nigeria Oluyemi, Aderemi Awolola, Nicholas Oyedeji, Olufemi Pan Afr Med J Research INTRODUCTION: Colorectal polyps are known precursors of colorectal cancers. The increase in utilization of colonoscopy in Nigeria has meant a rise in the recently reported incidence of these lesions. The aim of this study is to evaluate the clinicopathological profile of colorectal polyps biopsied during the inaugural 12 month period of colonoscopy from a private endoscopy suite in Nigeria. METHODS: This is a retrospective review of all the clients who had polyps diagnosed at colonoscopy over a 12 month period (August 2014 –July 2015) at a private endoscopy suite in Lagos, Nigeria. This analysis of prospectively collected data was performed using clinical information from the endoscopy logs and pathology database system of a private endoscopy suite based in Lagos, Nigeria. RESULTS: A total of 125 colonoscopies were carried out over the stated period. Of these, 14 individuals had a total of 18 polyps- 4 clients (28.6% of the persons with polyps) had two polyps each. The polyp detection rate was 11.2% while the polyp per colonoscopy rate was 14.4%. Of these clients, males were 10 in number; giving a male to female ratio of 2.5:1. Their ages ranged from 37 to 77 years (mean= 57.3 years). The presenting complaint at colonoscopy was hematochezia in 11 (78.6%), new onset constipation in 2 (14.2%) and peri-anal pain in 1 patient (7.1%). The polyps were distributed as follows; 2 (11.1%) in the ascending colon, 1 (5.6%) each in the transverse and descending colons, 8 (44.4%) in the sigmoid colon, 6(33.3%) located in the rectum. Hence, there was left sided (15 of 18= 83.3%) preponderance. Pathologically, tubular (adenomatous) polyp with or without low grade dysplastic changes was diagnosed in 6 of the 18 polyps (giving an adenoma detection rate of 4.8%), 4 (22.2%) were inflammatory polyps, 1 (5.6%) was malignant and another had the rare inflammatory fibroid polyp. Five (27.8%) of the specimens were reported as non-specific colitis. CONCLUSION: The study supports the present wisdom that polyps are clearly less prevalent in our environment when compared to the Western world. The increased prevalence with advancing age, in male subjects and of left sided lesions, is also in keeping with previous results from our environment. A case is also advanced for the increased deployment of endoscopy as a tool for the detection of these polyps and ultimately, the reduction of colorectal cancer in our population. The African Field Epidemiology Network 2016-08-30 /pmc/articles/PMC5267854/ /pubmed/28154688 http://dx.doi.org/10.11604/pamj.2016.24.333.9434 Text en © Aderemi Oluyemi et al. http://creativecommons.org/licenses/by/2.0/ The Pan African Medical Journal - ISSN 1937-8688. This is an Open Access article distributed under the terms of the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research
Oluyemi, Aderemi
Awolola, Nicholas
Oyedeji, Olufemi
Clinicopathologic review of polyps biopsied at colonoscopy in Lagos, Nigeria
title Clinicopathologic review of polyps biopsied at colonoscopy in Lagos, Nigeria
title_full Clinicopathologic review of polyps biopsied at colonoscopy in Lagos, Nigeria
title_fullStr Clinicopathologic review of polyps biopsied at colonoscopy in Lagos, Nigeria
title_full_unstemmed Clinicopathologic review of polyps biopsied at colonoscopy in Lagos, Nigeria
title_short Clinicopathologic review of polyps biopsied at colonoscopy in Lagos, Nigeria
title_sort clinicopathologic review of polyps biopsied at colonoscopy in lagos, nigeria
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5267854/
https://www.ncbi.nlm.nih.gov/pubmed/28154688
http://dx.doi.org/10.11604/pamj.2016.24.333.9434
work_keys_str_mv AT oluyemiaderemi clinicopathologicreviewofpolypsbiopsiedatcolonoscopyinlagosnigeria
AT awololanicholas clinicopathologicreviewofpolypsbiopsiedatcolonoscopyinlagosnigeria
AT oyedejiolufemi clinicopathologicreviewofpolypsbiopsiedatcolonoscopyinlagosnigeria