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Purification and characterisation of dsRNA using ion pair reverse phase chromatography and mass spectrometry

RNA interference has provided valuable insight into a wide range of biological systems and is a powerful tool for the analysis of gene function. The exploitation of this pathway to block the expression of specific gene targets holds considerable promise for the development of novel RNAi-based insect...

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Detalles Bibliográficos
Autores principales: Nwokeoji, Alison O., Kung, An-Wen, Kilby, Peter M., Portwood, David E., Dickman, Mark J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5267946/
https://www.ncbi.nlm.nih.gov/pubmed/28088361
http://dx.doi.org/10.1016/j.chroma.2016.12.062