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Inhibition of STAT3 by Anticancer Drug Bendamustine
Bendamustine (BENDA), which bears the bis(2-chloroethyl)amino moiety, is an alkylating agent that stops the growth of cancer cells by binding to DNA and interfering with its replication. However, the mechanism of action underlying its excellent clinical efficacy remains unclear. In this work, we rep...
Autores principales: | Iwamoto, Kazunori, Uehara, Yutaka, Inoue, Yukie, Taguchi, Kyoko, Muraoka, Daisuke, Ogo, Naohisa, Matsuno, Kenji, Asai, Akira |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5268383/ https://www.ncbi.nlm.nih.gov/pubmed/28125678 http://dx.doi.org/10.1371/journal.pone.0170709 |
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