Dysregulation of Systemic and Mucosal Humoral Responses to Microbial and Food Antigens as a Factor Contributing to Microbial Translocation and Chronic Inflammation in HIV-1 Infection

HIV-1 infection is associated with an early and profound depletion of mucosal memory CD4(+) T cells, a population that plays an indispensable role in the regulation of isotype switching and transepithelial transport of antibodies. In this study, we addressed whether the depletion of CD4(+) T cell in...

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Detalles Bibliográficos
Autores principales: Hel, Zdenek, Xu, Jun, Denning, Warren L., Helton, E. Scott, Huijbregts, Richard P. H., Heath, Sonya L., Overton, E. Turner, Christmann, Benjamin S., Elson, Charles O., Goepfert, Paul A., Mestecky, Jiri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5268400/
https://www.ncbi.nlm.nih.gov/pubmed/28125732
http://dx.doi.org/10.1371/journal.ppat.1006087

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