Cargando…

Diffusion and Binding of Mismatch Repair Protein, MSH2, in Breast Cancer Cells at Different Stages of Neoplastic Transformation

The interior of cells is a highly complex medium, containing numerous organelles, a matrix of different fibers and a viscous, aqueous fluid of proteins and small molecules. The interior of cells is also a highly dynamic medium, in which many components move, either by active transport or passive dif...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sigley, Justin, Jarzen, John, Scarpinato, Karin, Guthold, Martin, Pu, Tracey, Nelli, Daniel, Low, Josiah, Bonin, Keith
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5268495/ https://www.ncbi.nlm.nih.gov/pubmed/28125613 http://dx.doi.org/10.1371/journal.pone.0170414

Ejemplares similares

Prerecognition Diffusion Mechanism of Human DNA Mismatch Repair Proteins along DNA: Msh2-Msh3 versus Msh2-Msh6
por: Pal, Arumay, et al.
Publicado: (2020)

Cooperative Nuclear Localization Sequences Lend a Novel Role to the N-Terminal Region of MSH6
por: Gassman, Natalie R., et al.
Publicado: (2011)

Parameters of Reserpine Analogs That Induce MSH2/MSH6-Dependent Cytotoxic Response
por: Vasilyeva, Aksana, et al.
Publicado: (2010)

Cadmium inhibits mismatch repair by blocking the ATPase activity of the MSH2–MSH6 complex
por: Banerjee, Sreeparna, et al.
Publicado: (2005)

Cadmium inhibits mismatch repair by blocking the ATPase activity of the MSH2–MSH6 complex
por: Banerjee, Sreeparna, et al.
Publicado: (2005)

Mlh1 interacts with both Msh2 and Msh6 for recruitment during mismatch repair
por: DuPrie, Matthew L., et al.
Publicado: (2022)

Immunohistochemical Loss of the DNA Mismatch Repair Proteins MSH2 and MSH6 in Malignant Fibrous Histiocytomas
por: Ericson, Kajsa, et al.
Publicado: (2004)

Characterization and comparative sequence analysis of the DNA mismatch repair MSH2 and MSH7 genes from tomato
por: Tam, Sheh May, et al.
Publicado: (2009)

OTUB1 stabilizes mismatch repair protein MSH2 by blocking ubiquitination
por: Wu, Qiong, et al.
Publicado: (2021)

The properties of Msh2–Msh6 ATP binding mutants suggest a signal amplification mechanism in DNA mismatch repair
por: Graham, William J., et al.
Publicado: (2018)

An Evaluation of the Immunohistochemical Expression of Mismatch Repair Proteins (MSH2, MSH6, MLH1, and PMS2) in Prostate Adenocarcinoma
por: Javeed, Saira, et al.
Publicado: (2022)

Mismatch Recognition by Saccharomyces cerevisiae Msh2-Msh6: Role of Structure and Dynamics
por: Li, Yan, et al.
Publicado: (2019)

NPM-ALK mediates phosphorylation of MSH2 at tyrosine 238, creating a functional deficiency in MSH2 and the loss of mismatch repair
por: Bone, K M, et al.
Publicado: (2015)

The mismatch-repair proteins MSH2 and MSH6 interact with the imprinting control regions through the ZFP57-KAP1 complex
por: Acurzio, Basilia, et al.
Publicado: (2022)

DNA mismatch repair gene MSH6 implicated in determining age at natural menopause
por: Perry, John R.B., et al.
Publicado: (2014)

The Aspergillus fumigatus Mismatch Repair MSH2 Homolog Is Important for Virulence and Azole Resistance
por: dos Reis, Thaila Fernanda, et al.
Publicado: (2019)

Screening of the DNA mismatch repair genes MLH1, MSH2 and MSH6 in a Greek cohort of Lynch syndrome suspected families
por: Thodi, Georgia, et al.
Publicado: (2010)

Mismatch Repair Proteins and Microsatellite Instability in Colorectal Carcinoma (MLH1, MSH2, MSH6 and PMS2): Histopathological and Immunohistochemical Study
por: Ismael, Nour El Hoda S., et al.
Publicado: (2017)

Mismatch-repair protein MSH6 is associated with Ku70 and regulates DNA double-strand break repair
por: Shahi, Ankita, et al.
Publicado: (2011)

Mismatch Repair Protein Msh2 Is Necessary for Macronuclear Stability and Micronuclear Division in Tetrahymena thermophila
por: Wang, Lin, et al.
Publicado: (2023)

Risk for Hereditary Neoplastic Syndromes in Women with Mismatch Repair-Proficient Endometrial Cancer
por: dos Santos, Jennifer Thalita Targino, et al.
Publicado: (2023)

The DNA mismatch repair gene hMSH2 is a potent coactivator of oestrogen receptor α
por: Wada-Hiraike, O, et al.
Publicado: (2005)

Expression of hMSH2 protein of the human DNA mismatch repair system in oral lichen planus
por: Pimenta, Flávio Juliano Garcia Santos, et al.
Publicado: (2004)

Expression of human DNA mismatch-repair protein, hMSH2, in patients with oral lichen planus
por: LI, HAO-BO, et al.
Publicado: (2015)

Rare compound heterozygous mutations in gene MSH6 cause constitutive mismatch repair deficiency syndrome
por: Ling, Chao, et al.
Publicado: (2018)

Exceptional Response to Pembrolizumab in a Mismatch Repair-Deficient Aggressive Prostate Cancer with Somatic EPCAM, MSH2, and MSH6 Co-Deletion: A Case Report
por: Hoch, Dennis, et al.
Publicado: (2023)

Mismatch repair protein MSH2 regulates translesion DNA synthesis following exposure of cells to UV radiation
por: Lv, Lingna, et al.
Publicado: (2013)

Hypermethylation of mismatch repair gene hMSH2 associates with platinum-resistant disease in epithelial ovarian cancer
por: Tian, Hua, et al.
Publicado: (2019)

Ph2 encodes the mismatch repair protein MSH7-3D that inhibits wheat homoeologous recombination
por: Serra, Heïdi, et al.
Publicado: (2021)

Molecular mechanisms underlying the emergence of polygenetic antifungal drug resistance in msh2 mismatch repair mutants of Cryptococcus
por: Albehaijani, Samah H. I., et al.
Publicado: (2022)

Genetic Analysis Reveals the Prognostic Significance of the DNA Mismatch Repair Gene MSH2 in Advanced Prostate Cancer
por: Chang, Hao-Han, et al.
Publicado: (2022)

Andrias davidianus Ranavirus (ADRV) Genome Replicate Efficiently by Engaging Cellular Mismatch Repair Protein MSH2
por: Ke, Fei, et al.
Publicado: (2022)

TaMSH7: A cereal mismatch repair gene that affects fertility in transgenic barley (Hordeum vulgare L.)
por: Lloyd, Andrew H, et al.
Publicado: (2007)

Immunohistochemical analysis of expression and allelotype of mismatch repair genes (hMLH1 and hMSH2) in bladder cancer
por: Kassem, H Sh, et al.
Publicado: (2001)

DNA Polymerases as Potential Therapeutic Targets for Cancers Deficient in the DNA Mismatch Repair Proteins MSH2 or MLH1
por: Martin, Sarah A., et al.
Publicado: (2010)

BRCA2, EGFR, and NTRK mutations in mismatch repair-deficient colorectal cancers with MSH2 or MLH1 mutations
por: Deihimi, Safoora, et al.
Publicado: (2017)

Frequent loss of heterozygosity at the DNA mismatch-repair loci hMLH1 and hMSH3 in sporadic breast cancer
por: Benachenhou, N, et al.
Publicado: (1999)

Increased Hypermutation at G and C Nucleotides in Immunoglobulin Variable Genes from Mice Deficient in the MSH2 Mismatch Repair Protein
por: Phung, Quy H., et al.
Publicado: (1998)

Methotrexate induces oxidative DNA damage and is selectively lethal to tumour cells with defects in the DNA mismatch repair gene MSH2
por: Martin, Sarah A, et al.
Publicado: (2009)

Crosstalk between BRCA-Fanconi anemia and mismatch repair pathways prevents MSH2-dependent aberrant DNA damage responses
por: Peng, Min, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_0b5h2ar0cjsjg9s7ar8otnrnn1