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Activity Regulation by Fibrinogen and Fibrin of Streptokinase from Streptococcus Pyogenes
Streptokinase is a virulence factor of streptococci and acts as a plasminogen activator to generate the serine protease plasmin which promotes bacterial metastasis. Streptokinase isolated from group C streptococci has been used therapeutically as a thrombolytic agent for many years and its mechanism...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5268773/ https://www.ncbi.nlm.nih.gov/pubmed/28125743 http://dx.doi.org/10.1371/journal.pone.0170936 |