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Interleukin-21 Drives Proliferation and Differentiation of Porcine Memory B Cells into Antibody Secreting Cells
Immunological prevention of infectious disease, especially viral, is based on antigen-specific long-lived memory B cells. To test for cellular proliferation and differentiation factors in swine, an outbred model for humans, CD21(+) B cells were activated in vitro with CD40L and stimulated with purpo...
Autores principales: | Rahe, Michael C., Murtaugh, Michael P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5268775/ https://www.ncbi.nlm.nih.gov/pubmed/28125737 http://dx.doi.org/10.1371/journal.pone.0171171 |
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