Tumeur à cellules de Sertoli-Leydig de l’ovaire: à propos d’un cas chez une jeune fille de 22 ans

Sertoli-Leydig cell tumors are rare secreting mesenchymal and sex cord-stromal tumors. However, they constitute one type of tumor most often responsible for virilization syndrome. A definite diagnosis is provided by histological examination following surgical excision of the tumor. It has no characterizing features on ultrasonography, in spite of the strong clinical presumption. Like many neoplasias, prognosis is related to the degree of cellular differentiation and to the presence of heterologous elements. The aim of our study was to report the case of a 22-year old woman suffering from a real virilization syndrome secondary to non-epithelial Sertoli-Leydig cell tumor of the ovary. Poorly differentiated Sertoli-Leydig tumors have high malignant potential. Treatment is surgical; taxane-platinum combination chemotherapy is an interesting adjuvant. Prognosis after surgical resection is related to the risk of relapses.