Effects of early‐life exposure to THIP on brainstem neuronal excitability in the Mecp2‐null mouse model of Rett syndrome before and after drug withdrawal

Rett syndrome (RTT) is mostly caused by mutations of the X‐linked MECP2 gene. Although the causal neuronal mechanisms are still unclear, accumulating experimental evidence obtained from Mecp2 (−/Y) mice suggests that imbalanced excitation/inhibition in central neurons plays a major role. Several app...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhong, Weiwei, Johnson, Christopher M., Cui, Ningren, Oginsky, Max F., Wu, Yang, Jiang, Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5269412/
https://www.ncbi.nlm.nih.gov/pubmed/28108647
http://dx.doi.org/10.14814/phy2.13110

Ejemplares similares

Ejemplares similares