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Ankylosing Spondylitis Patients Have Impaired Osteoclast Gene Expression in Circulating Osteoclast Precursors

INTRODUCTION: Ankylosing spondylitis (AS) is typically characterized by focal bone overgrowth and also by systemic bone loss. We hypothesize that the increased osteoproliferation found in AS might be partially due to reduced ability of osteoclast precursors (OCPs) to differentiate into osteoclasts (...

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Detalles Bibliográficos
Autores principales: Perpétuo, Inês P., Caetano-Lopes, Joana, Vieira-Sousa, Elsa, Campanilho-Marques, Raquel, Ponte, Cristina, Khmelinskii, Nikita, Canhão, Helena, Ainola, Mari, Fonseca, João E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5269449/
https://www.ncbi.nlm.nih.gov/pubmed/28191455
http://dx.doi.org/10.3389/fmed.2017.00005