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Ankylosing Spondylitis Patients Have Impaired Osteoclast Gene Expression in Circulating Osteoclast Precursors
INTRODUCTION: Ankylosing spondylitis (AS) is typically characterized by focal bone overgrowth and also by systemic bone loss. We hypothesize that the increased osteoproliferation found in AS might be partially due to reduced ability of osteoclast precursors (OCPs) to differentiate into osteoclasts (...
Autores principales: | Perpétuo, Inês P., Caetano-Lopes, Joana, Vieira-Sousa, Elsa, Campanilho-Marques, Raquel, Ponte, Cristina, Khmelinskii, Nikita, Canhão, Helena, Ainola, Mari, Fonseca, João E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5269449/ https://www.ncbi.nlm.nih.gov/pubmed/28191455 http://dx.doi.org/10.3389/fmed.2017.00005 |
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