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Extracellular purines, purinergic receptors and tumor growth

Virtually, all tumor cells as well as all immune cells express plasma membrane receptors for extracellular nucleosides (adenosine) and nucleotides (ATP, ADP, UTP, UDP and sugar UDP). The tumor microenvironment is characterized by an unusually high concentration of ATP and adenosine. Adenosine is a m...

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Detalles Bibliográficos
Autores principales: Di Virgilio, F, Adinolfi, E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5269532/
https://www.ncbi.nlm.nih.gov/pubmed/27321181
http://dx.doi.org/10.1038/onc.2016.206