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GPX3 methylation in bone marrow predicts adverse prognosis and leukemia transformation in myelodysplastic syndrome

Epigenetic inactivation of GPX3 has been identified in various cancers including leukemia. Moreover, aberrant DNA methylation was also found as a dominant mechanism of disease progression in myelodysplastic syndrome (MDS). This study intended to explore GPX3 promoter methylation and its clinical rel...

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Detalles Bibliográficos
Autores principales:	Zhou, Jing‐Dong, Lin, Jiang, Zhang, Ting‐Juan, Ma, Ji‐Chun, Yang, Lei, Wen, Xiang‐Mei, Guo, Hong, Yang, Jing, Deng, Zhao‐Qun, Qian, Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2016
Materias:	Cancer Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5269561/ https://www.ncbi.nlm.nih.gov/pubmed/27891827 http://dx.doi.org/10.1002/cam4.984

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