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Prognostic impact of MutT homolog‐1 expression on esophageal squamous cell carcinoma

MutT homolog‐1 (MTH1) is a pyrophosphatase that acts on oxidized nucleotides and hydrolyzes 8‐oxo‐2’‐deoxyguanosine triphosphate in deoxynucleoside triphosphate pool to prevent its incorporation into nuclear and mitochondrial DNA, result in reduce cytotoxicity in tumor cells. MTH1 is overexpressed i...

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Detalles Bibliográficos
Autores principales:	Akiyama, Shingo, Saeki, Hiroshi, Nakashima, Yuichiro, Iimori, Makoto, Kitao, Hiroyuki, Oki, Eiji, Oda, Yoshinao, Nakabeppu, Yusaku, Kakeji, Yoshihiro, Maehara, Yoshihiko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2016
Materias:	Cancer Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5269568/ https://www.ncbi.nlm.nih.gov/pubmed/27917618 http://dx.doi.org/10.1002/cam4.979

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