Astrocyte-derived tissue Transglutaminase affects fibronectin deposition, but not aggregation, during cuprizone-induced demyelination

Astrogliosis as seen in Multiple Sclerosis (MS) develops into astroglial scarring, which is beneficial because it seals off the site of central nervous system (CNS) damage. However, astroglial scarring also forms an obstacle that inhibits axon outgrowth and (re)myelination in brain lesions. This is...

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Detalles Bibliográficos
Autores principales: Espitia Pinzon, Nathaly, Sanz-Morello, Berta, Brevé, John J. P., Bol, John G. J. M., Drukarch, Benjamin, Bauer, Jan, Baron, Wia, van Dam, Anne-Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5269585/
https://www.ncbi.nlm.nih.gov/pubmed/28128219
http://dx.doi.org/10.1038/srep40995

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