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Cold-inducible RNA-binding protein (CIRP) causes sepsis-associated acute lung injury via induction of endoplasmic reticulum stress

Cold-inducible RNA-binding protein (CIRP), released into the circulation during sepsis, causes lung injury via an as yet unknown mechanism. Since endoplasmic reticulum (ER) stress is associated with acute lung injury (ALI), we hypothesized that CIRP causes ALI via induction of ER stress. To test thi...

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Detalles Bibliográficos
Autores principales: Khan, Mohammad Moshahid, Yang, Weng-Lang, Brenner, Max, Bolognese, Alexandra Cerutti, Wang, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5269663/
https://www.ncbi.nlm.nih.gov/pubmed/28128330
http://dx.doi.org/10.1038/srep41363