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Discovering novel phenotypes with automatically inferred dynamic models: a partial melanocyte conversion in Xenopus
Progress in regenerative medicine requires reverse-engineering cellular control networks to infer perturbations with desired systems-level outcomes. Such dynamic models allow phenotypic predictions for novel perturbations to be rapidly assessed in silico. Here, we analyzed a Xenopus model of convers...
Autores principales: | Lobo, Daniel, Lobikin, Maria, Levin, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5269672/ https://www.ncbi.nlm.nih.gov/pubmed/28128301 http://dx.doi.org/10.1038/srep41339 |
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