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LPS-induced inflammatory response is suppressed by Wnt inhibitors, Dickkopf-1 and LGK974

In this study, LPS-induced inflammatory responses in BEAS-2B human bronchial epithelial cells and human umbilical vein endothelial cell (HUVEC)s were found to be prevented by Dickkopf-1 (DKK-1), a secreted Wnt antagonist, and LGK974, a small molecular inhibitor of the Wnt secretion. LPS-induced IκB...

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Detalles Bibliográficos
Autores principales:	Jang, Jaewoong, Jung, Yoonju, Kim, Youngeun, Jho, Eek-hoon, Yoon, Yoosik
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5269682/ https://www.ncbi.nlm.nih.gov/pubmed/28128299 http://dx.doi.org/10.1038/srep41612

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