Interplay with the Mre11-Rad50-Nbs1 complex and phosphorylation by GSK3β implicate human B-Myb in DNA-damage signaling

B-Myb, a highly conserved member of the Myb transcription factor family, is expressed ubiquitously in proliferating cells and controls the cell cycle dependent transcription of G2/M-phase genes. Deregulation of B-Myb has been implicated in oncogenesis and loss of genomic stability. We have identifie...

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Detalles Bibliográficos
Autores principales: Henrich, Sarah Marie, Usadel, Clemens, Werwein, Eugen, Burdova, Kamila, Janscak, Pavel, Ferrari, Stefano, Hess, Daniel, Klempnauer, Karl-Heinz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5269693/
https://www.ncbi.nlm.nih.gov/pubmed/28128338
http://dx.doi.org/10.1038/srep41663

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5269693/
https://www.ncbi.nlm.nih.gov/pubmed/28128338
http://dx.doi.org/10.1038/srep41663

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