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Discovery of Cancer Driver Long Noncoding RNAs across 1112 Tumour Genomes: New Candidates and Distinguishing Features

Long noncoding RNAs (lncRNAs) represent a vast unexplored genetic space that may hold missing drivers of tumourigenesis, but few such “driver lncRNAs” are known. Until now, they have been discovered through changes in expression, leading to problems in distinguishing between causative roles and pass...

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Detalles Bibliográficos
Autores principales: Lanzós, Andrés, Carlevaro-Fita, Joana, Mularoni, Loris, Reverter, Ferran, Palumbo, Emilio, Guigó, Roderic, Johnson, Rory
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5269722/
https://www.ncbi.nlm.nih.gov/pubmed/28128360
http://dx.doi.org/10.1038/srep41544